Gastric Cancer stem cells

Gastric epithelium is continuously regenerated by using gastric stem cells, which provide rise to diverse sorts of daughter cells, along with parietal cells, chief cells, floor mucous cells, mucous neck cells, and input endocrine cells. These days, it has been hypothesized that most of the cancers stem cells power cancer growth and metastasis. According to standard clonal evolution speculation, most cancer stem cells can initiate the tumor formation, self-renew, and differentiate into numerous styles of daughter cells. We evaluate here how important signaling pathways, such as hedgehog, need, Notch, epidermal increase thing, and bone morphogenetic protein signaling, may regulate the self-renewal and differentiation of gastric stem cells and gastric cancer stem cells.

Cancer Societies: Children's Cancer Association | French Society of Oncology Pharmacy | Belgian Association of Oncological Radiotherapy | Cancer Registry Bavaria | European Cancer Organization |

 

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